Journal: Materials

Article Title: Quantifying 3D Strain in Scaffold Implants for Regenerative Medicine

doi: 10.3390/ma13173890

Figure Lengend Snippet: Validation of localised strain against manually calculated values. Intra-Sample strain measurements calculated both using DVC software and manually calculated for one scaffold sample (Mech1), which underwent two levels of compression with in situ mechanical testing during micro-computed tomography (micro-CT) scanning .

Article Snippet: Cubic “Mech” scaffold samples ( n = 6) were mechanically compressed to 20% axial strain using a compression testing machine (Bose Electroforce Series III with 440 N load cell, TA Instruments, New Castle, DE, USA) in displacement control at a rate of 1 mm min −1 .

Techniques: Biomarker Discovery, Software, In Situ, Micro-CT

Journal: Materials

Article Title: Quantifying 3D Strain in Scaffold Implants for Regenerative Medicine

doi: 10.3390/ma13173890

Figure Lengend Snippet: ( a ) Volume renderings of scaffolds scanned using micro-CT imaging carried out under both unloaded and mechanical loading conditions for each sample. ( b ) Micro-CT cross-section accompanied by a magnified image demonstrating the 48 voxel subvolume size with a separate scale bar. “Mech” and “Imp” denote the two size of degradable scaffolds imaged and tested. The displayed strained images represent the higher loading levels applied to each sample . The compression platen by which mechanical load was applied to each scaffold is shown in blue. Note that the volume of interest included the whole sample for the cubic Mech1 sample but excluded the horizontal perimeter of the Imp samples. All micro-CT slice images have been reproduced with no image enhancement. Scale for both the volume renderings and micro-CT slices are as displayed next to the volume renderings.

Article Snippet: Cubic “Mech” scaffold samples ( n = 6) were mechanically compressed to 20% axial strain using a compression testing machine (Bose Electroforce Series III with 440 N load cell, TA Instruments, New Castle, DE, USA) in displacement control at a rate of 1 mm min −1 .

Techniques: Micro-CT, Imaging